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38 Iron overload Although iron is a helpful component of the human body and the major micronutrient in the human diet, involved in crucial cellular functions and metabolic processes, excessive iron increases the production of ROS, leading to cell dysfunction or death, tissue damage, and organ disease

doi: 10.1016/j.cmet.2018.05.012

Taken together, these observations argue that in ovarian cancer, lipid peroxidation execution depends on whether metastatic environments (omentum vs

Totally 83 (63.4%) of patients achieved histological regression at 78 weeks, and 48 (36.6%) were classified to the non-regression group

Mice with Hif1 msd were generated by crossing Hif1 flox mice with human skeletal actin mice with tamoxifen-inducible C re (JAX.org)

The study, published in Nature , shows that tumors can break down glutathione to support their growth, challenging long-held assumptions about its role in human health