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Arbutin (ARB), a natural phenolic glycoside, inhibits ferroptosis and alleviates non-alcoholic fatty liver disease by targeting the FTO/SLC7A11 axis, regulating gene methylation to enhance SLC7A11 expression [122]

For example, studies in rat models of CKD showed that cognitive decline correlated with serum indoxyl sulfate levels and bloodbrain barrier (BBB) disruption