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Moreover, selenium levels display a negative correlation with both LH and TT (80)

According to the dopamine-acetylcholine balance hypothesis, dopamine depletion leads to severe deterioration of basal ganglia circuit dynamics, resulting in overactivation of the cholinergic system and subsequent motor and cognitive impairments

Antioxidants 13(4):455 Kanda H, Yamawaki K (2020) Bardoxolone methyl: drug development for diabetic kidney disease

Sustainability 13(12):6849

Aging-related accumulation of senescent cells in the nervous system leads to neuronal dysfunction and exacerbates disease pathology (9), highlighting cellular aging as one of the most critical risk factors for neurodegeneration (4)

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