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37 Furthermore, even if CRF application protects against gastric ulcers, 38 exogenous administration of CRF can reproduce cardinal features of diarrhea predominant irritable bowel syndrome including anxiogenic behavior, enhanced visceral pain to colorectal distention, increased colonic mucus secretion, propulsive motility, development of watery stool/diarrhea, and increased colonic mucosal permeability facilitating bacterial translocation into colonic tissue

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For example, obesity-related systemic inflammation can interfere with the bodys ability to efficiently absorb, distribute, and utilize folate [46]

Final treatment options and eligibility should be reviewed by your provider during your appointment.