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Conclusion A series linear Ang IV analogues demonstrating improved metabolic stability and very high affinity to IRAP have been reported, e.g., the potent hexapeptides 11 (AL-11) and 12 (IVDE77) with Ki values of 7.6 and 1.7 nM, respectively, data to be compared with the Ki value of Ang IV of 62 nM in the same binding assay

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Consequently, in analogy to standard physically-covered insurance contracts, a supply offer submitted to M( n,T ) by a dispatchable power resource m electrically connected at grid location n should be a nodal two-part pricing contract that permits m to assure its revenue sufficiency by appropriate specification of the following two contractual terms: (i) a contract offer price (insurance premium) in lump-sum or amortized form ensuring m is compensated ex ante (i.e., prior to T ) for verified incurred reserve availability costs