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10.1186/s12890-020-1121-2 BMC Pulm Med

[413] demonstrated the antifibrotic effects of RES on intestinal smooth muscle cells from a CD rat model, finding that this compound decreased cell numbers through cell cycle arrest and apoptosis, and reduced collagen synthesis and procollagen mRNA expression

Peptide therapy uses these naturally occurring compounds to signal specific biological functions, such as improving metabolism, repairing tissue, stimulating collagen, and balancing hormones

These include larger tumor size, higher tumor grade, and increased lymph node involvement (, )

An intriguing observation is depicted by the blue dashed line in Fig