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Worms were initially transferred from Novosphingobium L76 to NGM plates supplemented with 50 g/ml of kanamycin for one generation, then back to E

Research shows treated animals lost an average 5.1% body weight, 30% reduction in adipocyte size and 35% decrease in white adipose tissue mass

All of these steps have an important significance, as indicated above, but the key aspect is perhaps the step via vitamin B12-dependent methionine synthase which links the entire methionine cycle directly to the folate cycle

Signs of B12 deficiency include fatigue, brain fog, poor concentration, and low energy

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