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However, in the 1950s, Rebecca Gerschman [1] and her colleagues noticed that oxygen poisoning resembled damage caused by X-rays and proposed the involvement of free radicals, which greatly advanced our understanding of the mechanism [2]

Biochimie 95(8):16291639 Tripathi D, Jena G (2010) Astaxanthin intervention ameliorates cyclophosphamide-induced oxidative stress, DNA damage and early hepatocarcinogenesis in rat: role of Nrf2, p53, p38 and phase-II enzymes

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Reversal of age-related cognitive impairments in mice by an extremely low dose of tetrahydrocannabinol

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