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Conversion is fine for most healthy younger adults, but can be less efficient in people with MTHFR genetic variants (an estimated 25 to 40% of the population carries at least one variant), people with liver function decline (more common with age), and smokers and former smokers

Don't eat or drink anything after midnight the evening before the procedure

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Utilizing a suitable sterile automated compounding device or dispensing pin for accuracy, aseptically transfer each 10 mL dose into a plastic or glass bottle containing at least 500 to 1,000 mL intravenous parenteral nutrition solution containing dextrose or saline

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