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In 2004, aromatase inhibitory activity of SB in leiomyoma cells was reported and the enzyme was inhibited in a time- and dose-dependent manner (Lee et al., 2004b)

We suggest that, with encouraging evidence of therapeutic effects and increasing insights into the mechanisms of action, randomized controlled trials should be conducted to elucidate a foundation for the clinical use of the KD

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It dampens inflammatory cytokine signaling

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