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This may be due to the higher catalytic efficiency of COMT in the formation of 4-methylated estrogens than 2-methylated estrogens and the difference in the kinetics of the two reactions 27

The transcriptomic results were verified by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) analysis (Fig

Autism spectrum disorder (ASD) affects 1 in 36 children in the United States, a number that continues to climb. Globally, estimates suggest that approximately

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This is of clinical relevance as TPP levels can be measured by addressing the activity of transketolase in a blood sample