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In addition, mucus contains secretory immunoglobulin A, antimicrobial products, peptides trefoil (trefoil factor family, TFF), cathelicidins, and ribonucleases, which are responsible for reinforcing the physical separation of the microbiota, forming a gradient from the epithelium to the lumen [11]

Long-term outcome of 4 patients with transcobalamin deficiency caused by 2 Novel TCN2 Mutations

Duran, A

As with vitamin B9 deficiency, vitamin B12 deficiency is also associated with megaloblastic anaemia due to the vitamins vital role in DNA synthesis (Socha et al, 2020)

Nat Cell Biol (2020) 22(10):1197210

Researchers planning new work should review the most current literature before designing protocols, with attention to the gap between preclinical breadth and clinical-trial depth