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Duzel A, Vlainic J, Antunovic M, et al

Oxidative stress in synapse development and function

Reverse transcription-quantitative PCR was also used to quantify the levels of mRNA produced in the tissue from the polymerase gamma (POLG), polymerase gamma 2 (POLG2), and mammalian mitochondrial transcription factor A (TFAM) genes

Map3k14 deficiency disrupts NADPH production, induces the accumulation of ROS in cells, and eventually leads to the autophagic degradation of hexokinase 2