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In an earlier study, we showed, using an immunocompetent mouse model of endometriosis, generated with intraperitoneal administration ( ip ) of endometrial fragments null for the progesterone receptor interacting protein Krppel-like Factor 9 (KLF9), that high-fat diet (HFD) promoted endometriosis progression in the absence of ovarian dysfunction, insulin resistance, and significant increase in bodyweight (Heard et al., 2016)

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Some approved drugs are themselves peptides, such as: Insulin GLP-1 receptor agonists Calcitonin Oxytocin Such success has spurred scientists to look into even more potential therapeutic peptides

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[Google Scholar] 140.Omi R, Kurokawa S, Mihara H, Hayashi H, Goto M, Miyahara I, Kurihara T, Hirotsu K, Esaki N