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Frontiers Metabolic interactions in the brain: the crucial roles of neurons, astrocytes, and microglia in health and disease Proposed roles of system xc. Three main roles have been proposed for Download Scientific Diagram Thinking Outside the Cleft to Understand Synaptic Activity: Contribution of the Cystine Glutamate Antiporter (System xc) to Normal and Pathological Glutamatergic Signaling ScienceDirect Cystine glutamate antiporter System xc deficiency impairs insulin secretion in mice Diabetologia Springer Nature Link The heterodimeric glutamate cystine antiporter system Xc xCT (SCL7a11) Download Scientific Diagram Molecular basis for redox control by the human cystine glutamate antiporter system xc Nature Communications

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