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The REDEFINE 1 trial found that when evaluating the treatment effect regardless of whether patients stayed on treatment, those treated with CagriSema achieved weight loss of 20.4% (from an average baseline body weight of 236 lb) at 68 weeks versus 3.0% (from an average baseline body weight of 235 lb) for the placebo group which was statistically significant

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Protocol Adherence FOXO4-DRI's D-amino acid structure provides extended stability, but the intermittent dosing schedule (3 days on, 4 days off) is designed around the biology of clearance and recovery