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(Continued) Species a Strain Measured end-point b Test conditions Activation c Induction d Results e Reference E

Human long-term safety data remain limited

The absence of this, or vague, unhelpful responses, is another indicator of a potentially unreliable source

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22 Hierarchical clustering or principal component analysis (PCA) was performed on microarrays from the Hou database 19 using Cluster (Michael Eisen of UC Berkley) and Java Treeview 23 or SimcaP (MKS Data Analytics), respectively