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Taken together, these findings indicate that NSBSO treatment leads to GSH depletion and inhibition of GSH biosynthesis, which in turn inhibits GPX4 activity and resulting ferroptosis in 4T1 cells

doi: 10.1139/bcb-2015-0030

MCTR1 inhibits ferroptosis by promoting NRF2 expression to attenuate hepatic ischemia-reperfusion injury

This glutathione leaves the liver and is transported to your cells

Arterioscler Thromb Vasc Biol 34:751758 Nishizawa H, Matsumoto M, Chen G, Ishii Y, Tada K, Onodera M, Kato H, Muto A, Tanaka K, Igarashi K (2021) Lipid peroxidation and the subsequent cell death transmitting from ferroptotic cells to neighboring cells

Current scientific evidence does not suggest that glutathione directly causes pimples or acne breakouts