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In the United States alone, the economic burden of PD exceeded $52 billion in 2020, with caregivers losing an average of $19,000 in annual income due to reduced work hours or job loss (Chaudhuri et al., 2024)

Available online at: www.fda.gov/regulatory-information/search-fda-guidance-documents/testicular-toxicity-evaluation-during-drug-development (Accessed December 19, 2024)

Indications: as monotherapy, or adjunctive therapy for virtually all type seizures associated with epilepsy for short term treatment of manic episodes associated with bipolar disorder

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However, there were no patients with adjudicated serious adverse events of atrial fibrillation in the Reclast treatment group