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These individuals do not simply "sleep it off." They require emergency medical care, often including mechanical ventilation to support breathing, intravenous fluids to manage dehydration and electrolyte imbalances, and medications to stabilize heart function

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[197] Notably, infection is the second leading cause of death in hemodialysis patients

Summary: Yes, vitamin B12 is a water-soluble vitamin, though uniquely it can be stored in the liver for several years despite being excreted through urine when consumed in excess

Lack of sleep