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National Institutes of Health for individuals with a BMI of 30 kg/m2 who also have comorbidities such as diabetes, hypertension, dyslipidemia or sleep apnea (22)

2000 in Hormone Research showed that 21-day oral AOD-9604 (500 mcg/kg/day) reduced body weight gain by roughly 50% in obese Zucker rats with no insulin sensitivity penalty

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Thus, calcium supplementation in patients with T2D can help prevent vitamin B12 deficiency associated with metformin intake and improve glycemic control

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