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While direct evidence from silicosis models is still needed, this mechanistic insight suggests that targeting ferroptosis via stem cell paracrine signaling could represent a promising therapeutic approach against silica-induced pulmonary fibrosis

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Betzel, Alessandra Griffa, Patric Hagmann, and Bratislav Mii

Co-Targeting E-Selectin/CXCR4 with GMI-1359 Facilitates AML Stem Cell Mobilization and Protects BM Niches from Anti-Leukemia Therapy

People with compromised immune systems, chronic respiratory conditions, or genetic susceptibilities are particularly vulnerable