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One study of post-menopausal women with PCOS using 4g/day of myo-inositol also found a reduction in fasting glucose, fasting insulin and HOMA-IR ( Inositol supplements in postmenopausal women with metabolic syndrome 2012 )

Carmen JM, Shrivastava S, Lu Z, Anderson A, Morrison EB, Sankhala RS, et al

Zahid M, Gaikwad NW, Rogan EG, Cavalieri EL

(NIH) Regular use of milk thistle may help maintain more youthful-looking skin while providing natural protection against environmental damage

Data availability The mRNA-Seq data generated in this study have been deposited in the GEO database under the accession number GSE248642 ( The lipidomes generated in this study are provided in the Source Data