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The hydroxylation of proline residues enables ubiquitination via the von Hippel-Lindau E3 ligase complex [23]

Antioxidant additives using substances that delay or prevent the oxidation of cellular substrates have demonstrated the capacity to protect the human body against oxidative damage

This can be accomplished by including plenty of plant-forward ingredients like fruits, vegetables, and nuts/seeds in your diet

Accessed 20 March 2022 Polegato BF, Pereira AG, Azevedo PS, Costa NA, Zornoff LAM, Paiva SAR, Minicucci MF (2019) Role of thiamine in health and disease

Department of Health, Education and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health

This is why it has long attracted interest in endocrinological and metabolic research, particularly in areas such as the growth hormone axis, regeneration, body composition, metabolism, and neurobiology