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We are talking about a fundamental biological necessity

Secondly, the identification of hormetic substances in food is currently limited, often focusing on a few well-characterized compounds, leading to a likely underestimation of the full spectrum of beneficial food-derived hormetins

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Immunity 43 , 161174 (2015)

This change involves an abnormal increase in levels of certain chemicals in the brain that signal pain (neurotransmitters)

Epigenetic modifications also drive the resistance to immunotherapies