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In LC, autophagy exerts context-dependent effects

This dye exhibits two distinct emission peaks: red fluorescence from J-aggregates, indicative of hyperpolarized mitochondria (high membrane potential), and green fluorescence from JC-1 monomers, associated with depolarized mitochondria (low membrane potential)

Some studies in animal models raised concerns about potential cancer risks with prolonged use, leading to its discontinuation in pharmaceutical research

MedchemExpress) at molar ratios of 50:38.5:10:1.5 according to the manufacturers protocol

Thus, the alteration of GABA-glutamate equilibrium resulted in a sustained high GABA/glutamate ratio in JEV-infected brain, which is secondary to the aberrant glutamine-glutamate metabolism described before