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Association of assisted reproductive technology and multiple pregnancies with the risks of birth defects and stillbirth: A retrospective cohort study

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At 48 weeks, mean percentage changes in body weight from baseline were approximately: In the 12 mg arm, roughly 100% of participants achieved at least 5% body-weight loss, about 83% reached 15% loss, around 63% achieved 20% loss, and approximately 26% crossed the 25% threshold

Interestingly, the neural crest lineage arises from the pluripotent epiblast prior to definitive germ layer formation 44,45