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Description

B-cell lymphoma 2 (BCL-2) is a mitochondrial membrane protein that regulates apoptosis by blocking Bax- and Bak-mediated oligomerization in the outer mitochondrial membrane (OMM), thereby preventing cytochrome c release and caspase activation ( 2+ signaling, further contributing to the control of apoptosis ( Previous studies have highlighted the role of BCL-2 in intestinal epithelial injury