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Description

Its epidemiology shows marked geographic variation: incidence is highest in North America and Western Europe (920 cases per 100,000 person-years) but is rising rapidly in regions historically considered low risk, including parts of Asia and South America ( Pharmacologic management of UC aims to control inflammation and induce and maintain remission

doi: 10.1038/s41573-022-00579-0

Durazzo A, Nazhand A, Lucarini M, et al

Boie Y, Rushmore TH, Darmon-Goodwin A, Grygorczyk R, Slipetz DM, Metters KM, Abramovitz M (1994) Cloning and expression of a cDNA for the human prostanoid IP receptor

DTCs can reduce cytotoxicity and prevent DNA damage and cell death through increasing the activity of aldehyde dehydrogenase (ALDH) and overcoming the accumulation of toxic intermediates, aldehydes (98)