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Contrary to the aforementioned editorial claims, BTIs are often associated with worse outcomes, including severe or critical illness in ~11% of cases, linked to comorbidities like cardiovascular disease, and mortality rates around 0.9%substantially higher than the 0.03-0.05% infection fatality rate for natural SARS-CoV-2 infections in similar populations

Several medications can interact with vitamin B12 or affect its absorption, including: Metformin (diabetes medication) Proton pump inhibitors and H2-receptor antagonists (acid-reducing medications) Specific antibiotics (neomycin, chloramphenicol) Colchicine (gout medication) Aminosalicylic acid Nitrous oxide (inactivates vitamin B12) Allergic reactions to vitamin B12 are extremely uncommon but can occur