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Another approach involves modifying Lactobacillus plantarum to produce native GLP-1, which was shown to improve metabolic parameters, reduce inflammation, and restore -cell function in HFD/STZ mouse models of T2DM (Hu et al., 2023)

These transformations are mediated by a variety of colonic bacteria, including Clostridium spp., Flavonifractor plautii , and Eubacterium ramulus ( in vitro fecal fermentation model, Roowi et al

HDACs and HDAC inhibitors in cancer development and therapy

The concept of TXN inhibitors has emerged as an innovative domain within the realm of anti-cancer agents, imparting the capability to stimulate the generation of ROS