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brand name: Purinethol, Purixan) Tofacitinib (brand name: Xeljanz) This is an oral medication approved for moderate to severe UC that works by inhibiting the Janus kinase (JAK) protein family, which consists of JAK 1, 2 and 3 and the related kinase tyrosine kinase 2

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In laboratory research, it is used to study receptor-mediated signaling in pituitary models and downstream IGF-1 pathway activity

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