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and matching orthotopic PDX models, we monitored a pronounced reduction of efficacy in the orthotopic setup

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Villus-derived organoids initially display an irregular shape due to the structural pull from the villus fragments, but progressively acquire a spheroidal morphology similar to crypt-derived collagen organoids upon continued culture (Fig

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Once fully attached, cells were incubated with serum-free medium (MCDB 131 medium) for 24 h

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Does oral apigenin have real potential for a therapeutic effect in the context of human gastrointestinal and other cancers

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