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Where results are borderline, measurement of methylmalonic acid (MMA) or holotranscobalamin (active B12) may help clarify the picture, as recommended in NICE CKS guidance on B12 and folate deficiency anaemia

In-house testing is appropriate for process control during manufacturing, where continuous, rapid testing is needed

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In IBD, the physiological passage of immunoglobulins may have a deleterious effect upon the foetus with potential long-term implications (e.g

How often should B12 injections be administered for deficiency treatment