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38 During aging, elevated mtDNA mutations and impaired protein homeostasis synergistically induce excessive reactive oxygen species (ROS) production, resulting in oxidative stress and mitochondrial autophagy impairment, eventually perpetuating a vicious cycle of mitochondrial dysfunction

(2010) 5:e11302

Drug metabolism and disposition the biological fate of chemicals 34, 16061614

Benefits of Glutathione: 1

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The study concluded that feeding mice with a selenium-deficient diet for 6 months led to the depletion of renal GPx activity by 17% but did not alter renal radiosensitivity as compared to the mice fed with a selenium-adequate diet