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These studies indicate the potential of utilizing the de novo pathway, a less extensively studied pathway, as a therapeutic strategy for metabolic diseases Barth syndrome is a rare disease caused by mutations in the tafazzin gene encoding for cardiolipin (CL), a phospholipid specific for the mitochondria 303

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Ten days after transplantation, the animals were anesthetized with sevoflurane (Maruishi Pharmaceutical), and their livers were removed, embedded in super-cryoembedding medium and frozen quickly in liquid nitrogen

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