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Am J Transplant (2011) 11:93646

This may be partly explained by the MCT4 expression as a major exporter of lactate, which showed higher expression levels on the tumour epithelium compared to the stroma (positive cell counts in medial and lateral tumour regions respectively - epithelium: 77% and 94%

Concurrently, non-redox effects of NAD + , where NAD + transport, biosynthesis, and catabolism enable diverse roles in the regulation of energy transduction, in cell signaling, as a post-translational modifier, and as an epigenetic mediator have become apparent (3)

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This masking protein prevents signal transduction and leads to decreased activity

Hypocitraturia: This refers to low levels of citric acid in the urine