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Elsevier, pp 4173

The following grades were used to determine the macroscopic score: 0 for non-visible changes,1 for mild erythema and mucosal edema or erosion, 2 for moderate edema, bleeding, or erosion, and 3 for severe edema, ulcers, or necrosis

The choice often depends on whether the primary concern is local GI healing versus systemic chronic inflammation affecting multiple systems

These transposable elements include transposons and retrotransposons, such as endogenous retroviruses, which can essentially cut and paste into any portion of the human genome