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doi: 10.1038/tp.2014.87 109 ProvenzanoGGilardoniAMaggiaMPernigoMSgadPCasarosaSet al

However, these established mechanisms have significant limitations

As BURP-domain cyclases are scaffold-generating enzymes in plant specialized metabolism that are physically connected to their substrates in the same polypeptide, we introduce a bioinformatic method to mine plant genomes for precursor-peptide-encoding genes by detection of repetitive substrate domains and known core peptide features

10.1038/nm.4068 3 BennikeT

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