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Am J Med Genet 44:5256 Brooker G, Jeffery J, Nataraj T, Sair M, Ayling R (2007) High anion gap metabolic acidosis secondary to pyroglutamic aciduria (5-oxoprolinuria): association with prescription drugs and malnutrition

Production of transcriptomics data set by RNA-Seq

Proteomics data are available via ProteomeXchange with the identifier PXD042314 ( Abbreviations ASD: autism spectrum disorders CNS: central nervous system CGI: Clinical Global Impression DEGs: differentially expressed genes DEPs: differentially expressed proteins EV: extracellular vesicles FC: fold change GCP: Good Clinical Practice GO-BP: Gene Ontology-Biological Process GSEA: Gene Set Enrichment Analysis IRB: Institutional Review Board LR: ligandreceptor LCMS/MS: liquid chromatography tandem mass spectrometry MCID: minimal clinically important difference NK: natural killer NTA: nanoparticle tracking analysis PBMCs: peripheral blood mononuclear cells PBS: phosphate-buffered saline PD: Proteome Discoverer pDCs: Plasmacytoid dendritic cells PHGDH: Phosphoglycerate dehydrogenase SEM: standard error of the mean TADA: Transmission and de novo Association WGCNA: Weighted gene co-expression network analysis References Maenner, M

1 2 Neurochemistry

ElNashar, N

Anti-inflammatory Action: It's been observed to modulate inflammation, a key factor in both acute injury and chronic conditions