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2003 Niihara Y, Macan H, Eckman JR, Koh H, Cooper ML, Ziegler T, Razon R, Tanaka K, Stark CW, Johnson CS (2014) L-Glutamine Therapy Reduces Hospitalization for Sickle Cell Anemia and Sickle -Thalassemia Patients at Six Months A Phase II Randomized Trial

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Generation of KO and knockdown cell lines Optimized sgRNA oligonucleotides 64 were cloned into lentiCRISPRv2 (ref

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Prevention : Include B12-rich foods like meat, dairy, and eggs in maternal and infant diets