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For example, malonylation introduces an acyl group with a similar molecular size to butyrylation, but the malonyl group has an anionic carboxylate group

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Maes M, Meltzer HY, Bosmans E, Bergmans R, Vandoolaeghe E, Ranjan R, et al

Hyperbranched polymers: Recent advances in photodynamic therapy against cancer

Nat Rev Immunol 9 : 418428

However, any attempt to make functional predictions based on the localization of an immune cell must take into consideration that several immune cell subtypes/phenotypes exist, which fulfill different and in some cases, for example, M1 and M2like macrophages, even opposing functions (Murray & Wynn, 2011