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The evidence base is almost entirely preclinical: rodent models consistently show accelerated tissue repair, gut healing, and neurological protection, but human RCT data remains largely absent

Older adults are also more likely to take medications that can interfere with B12 absorption, Manson says

Consult a licensed healthcare professional before using any injectable medication

What the Human Data Show Long-term human data for Epithalon are limited compared with small-molecule drugs, but several cohort studies, some with more than twelve years of follow-up, have reported measurable improvements in melatonin rhythm, circadian function, glucose tolerance, and reductions in all-cause mortality among older patients