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The main regulatory proteins of LIP include transferrin receptor (TFRC) and ferritin (FPN)

Different from brown adipose tissue, sensory nerves in white adipose tissue are more involved in regulating the synthesis and decomposition of fat, thereby regulating the homeostasis of fat metabolism, and this may be achieved by inhibiting sympathetic nerves

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In the luteal phase, Ca [45,46], Zn [47,48], Fe [49,50,51,52,53], and magnesium (Mg) [54,55] collectively support endometrial function [56]

CDCA is an endogenous ligand for FXR, and its activation can reduce lipid absorption in intestinal cells and control lipid synthesis in liver cells ( in vitro studies have shown that simvastatin undergoes bioaccumulation in gut bacteria and is biotransformed by bacterial enzymes (e.g., from Lactobacillus and Bifidobacterium ), leading to delayed absorption and reduced concentration of simvastatin (71), ultimately weakening the lipid-lowering efficacy of simvastatin