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Camilleri, M., Parkman, H

doi: 10.3390/molecules26040985 [DOI] [PMC free article] [PubMed] [Google Scholar] 266

The construction of each model followed a systematic approach to ensure rigorous evaluation and validation

When you're conducting research, you're not just looking at isolated mechanisms

In addition, this uncontrolled immune response could be potentiated by impaired pituitary function due to autoimmune damage, which manifests in symptoms varying in severity, such as fatigue, orthostatic hypotension and sleep disturbances, depending on the degree of pituitary damage (42, 59)