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FDA described the clinical evidence as inconclusive and preliminary and identified product-characterisation, aggregation, immunogenicity and safety uncertainties

Nature 494 , 201206 (2013)

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Thereby, as a part of the counteraction of the symptoms of severe vascular and multiorgan failure syndrome, and of progressing Virchow counteraction, there was counteraction of severe lesions of the brain, heart, lung, liver, kidney and gastrointestinal system, progressing thrombosis, in peripheral and central arteries and veins [5,6,66,71,72,73,74,75,76,77,78,79,80,81,82], intracranial (superior sagittal sinus), portal and caval hypertension, and aortal hypotension, all of which were attenuated or eliminated

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PICO, Population, Intervention, Comparator, Outcome