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The trial endpoints include both traditional AD outcomes (e.g., cognition, brain imaging, AD fluid biomarkers) and gold standard aging measures (e.g., frailty, physical function, epigenetic age, etc.)

Zhang Z, Gao J, Yuan L, Duan B, Yang H, Ma L

It should not include personal use instructions or clinical dosing recommendations

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Then, we discuss the broader research and clinical literature on longevity to decide if supplementation with NAD, NR, NMN, rapamycin, or resveratrol can indeed extend lifespan

Weve outlined the benefits of a B12 energy shot, but lets go into how it actually works