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It is clear from the studies going back many decades that ascorbate and glutathione can be redox-coupled

The applied HPLC equipment contained a Shimadzu (Kyoto, Japan) model LC-9A HPLC pump with Shimadzu FCV-AL proportioning valve, a Knauer (Bad Homburg, Germany) model A0263 manual injector, a Merck cartridge LiChrosphere 100RP-18 column (250 3.4 mm), a Shimadzu model RF-535 fluorescence monitor (excitation at 365 nm, emission at 430 nm) and Shimadzu Class-VP software (version 4) for pump control, data acquisition and analysis

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What makes Pickart's discovery particularly elegant is its biological plausibility

After SCI, the expression levels of DMT1 and TFR in the white matter of the spinal cord are significantly increased, resulting in iron deposition