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Description

First-in-human study testing a new radioenhancer using nanoparticles (NBTXR3) activated by radiation therapy in patients with locally advanced soft tissue sarcomas

Upon small-scale combinatorial screenings, three molecular building blocks, i.e., -cyclodextrin-modified branched polyethyleneimine, adamantane-coated PEG, and polyamidoamine dendrimer, were integrated