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The molecule, initially marketed for pediatric use, was withdrawn as a therapeutic entity but gained renewed attention for its potential in GHRT for aging adults

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Discussion This 7T 1 H-MRS study has demonstrated that compulsivity and clinical compulsive symptoms are related to neurochemical indices in the anterior cingulate cortex and supplementary motor area of the frontal lobes, suggestive of an altered excitatory/inhibitory (E/I) balance between the neurometabolites Glu and GABA in these regions

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Supplementation may be contraindicated in hypothyroidism patients (Benvenga 2005)

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